I dig science. A big part of the reason why is because I really enjoy researching the “whys” of things. While my father always liked that about me, my mother oftentimes had something slick to say about it (that’s another message for another time, chile). To me, it’s whatever. For better or for worse, I’m simply not someone who accepts that the sky is blue “just because” — put it on my daddy’s DNA, I guess; with no apologies in place, I almost always want to know why something is the way that it is.
And since I spend so much of my time working with couples and writing on relationships, I’m sure no one is shocked that I’ve done my due diligence when it comes to figuring out what is really going on in the minds of humans whenever they are hyped about being in love. While on the surface level, it might seem like I’m being cynical, I’m actually not. It’s more about…well, again, I’ve been working with couples and writing about relationships for so long at this point that I think it’s important for folks to know the difference between an “emotional surge” and a truly wise love decision — and being aware of the role that the brain plays when we think that we’re in love with someone? That can help to bring some perspective and clarity into all of this.
So, whether you’re in something new and you’re currently on cloud nine, you’ve been in something for a while now and you’re wondering if you’ve “lost that loving feeling” or if you’re borderline on the verge of self-sabotage or, you’re like me, and you simply like to know random information just because — I’ve got 10 things that might be of interest to you as far as what science says love can literally do to you on the mental tip.
It’s fascinating stuff, indeed.
1. Dopamine Gets Activated
It’s pretty interesting that dopamine is a type of neurotransmitter that plays a significant role in things like how you are able to experience pleasure or create memories because both of those are quite relevant when you’re in love with someone. Well, according to science, when you feel like you truly love an individual, dopamine gets activated on a whole ‘nother level to the point where you not only feel euphoric but, it’s at the level of what alcohol or a cocaine high can produce (have mercy!) I’m not exaggerating, either.
In fact, Medical News Today once published an article entitled, “Falling In Love Hits The Brain Like Cocaine Does.” Hmm…makes you wonder if some people run up outta there marriages, not because there’s really anything “wrong”; it’s just that they have crashed from their “cocaine high” and no one prepared them for how to handle it (get into premarital counseling, engaged folks; it makes all the difference in the world!). Also, as far as dopamine goes, when men are “falling” for a woman, it’s dopamine and vasopressin that increase, while, for women, it’s dopamine and oxytocin. During sex, vasopressin drops in men, while oxytocin increases when a woman climaxes. The more you know.2. Euphoria Increases
Let’s go a little bit deeper into the whole euphoria thing. At the end of the day, euphoria is about intensity. I mean, a part of the reason why the series Euphoria has been so popular (and jarring) is that it shows how drug abuse can put people into a euphoric state — at first in a pleasurable way and eventually on a devastating level. When it comes to love, some experts say that three stages transpire when you feel like you’re in a love-related euphoric state: arousal, attraction, and attachment. And you know what? If you aren’t intentional about doing what Ben Franklin once said (“If passion drives you, let reason hold the reins.”), you could find yourself being on a roller coaster of emotions without having a relationship that consists of much stability. Yeah, euphoria increasing can be problematic as hell if you don’t get all of what comes with that.
3. Oxytocin Surges
When it comes to the articles that I’ve written on love, sex, and relationships on this platform, I don’t know if there’s any hormone that I’ve shouted out more than oxytocin. That’s because there are countless amounts of intel supporting the fact that it bonds people through things like hand-holding, cuddling, kissing, and definitely sex. That’s why some experts say that oxytocin can cause people to become “single-minded” about a person, it can cultivate feelings of trust, and it can literally create physiological changes that cause you to seek out your love interest.
This is a part of the reason why, when people declare that they are “in love” after say, a one-night stand, my mind immediately thinks, “Eh. Sounds more like an oxytocin surge.” You don’t know them well enough to love them; you can “love” how they make you feel, though. It’s essential to know the difference.
4. Fear Decreases
Now, this is an interesting one. Something else that science says happens when people are in love is the neural pathway that is associated with things like fear and judgment. It actually deactivates itself (chile…CHILE). Yep, some studies reveal that the part of your brain that encourages you to make “critical assessments” of individuals. When you feel like you love them, that shuts down. As a direct result, in walks the rose-colored glasses, and out goes the red flags. And that’s why, when I recently read that a particular actor didn’t heed some warnings from her friends regarding her new relationship, I literally shook my damn head.
When you’re all in love, especially in the beginning stages, having folks around who don’t feel the same ways about the person as you do can actually help you out in the long run, so long as they are good friends with a solid track record, they are going to notice some things that your neural pathway is keeping you from paying close attention to. Yeah, y’all be careful out there.
5. Your Prefrontal Cortex Slows Down
Speaking of desensitized senses, something else that transpires when you’re caught up in someone is your prefrontal cortex becomes sluggish. Why is this problematic? Well, that’s where the logical part of your brain is housed. This means that when you love someone, you may not be the best at making sound and practical decisions. Although I don’t agree with an article that said this means that love is illogical (love is sound, sane, and stable; it’s folks who jack relationships up…not love), I do think all of this is a reminder that you must rely on more than just how someone makes you feel when you’re trying to decide who to build a life with. Moving on.
6. Your Hypothalamus Revs Up Your Sex Hormones
I don’t know about y’all, but I don’t know too many people who aren’t attracted to the object of their love and affection. And so, when you do fall in love, something else that happens is the part of your brain known as the hypothalamus stimulates your ovaries while it also stimulates your man’s testicles — and that is what makes you feel an overwhelming feeling of desire (i.e., lust) for your partner.
7. Your Brain’s “Reward Circuit” Lights All the Way Up
Speaking of longing for your partner, three parts of your brain — the amygdala, the hippocampus, and the prefrontal cortex — are known as its “reward circuit,” and whenever you even speak about your bae, this is the part of your brain that lights up like a Christmas tree. Something that’s really interesting about this particular point is, that while this is happening, your serotonin levels typically drop.
Why does this matter? Well, serotonin helps to keep your anxiety levels in balance, and it also helps you to regulate your appetite(s). This would automatically cause me to believe that people who struggle with love addiction probably have a low level of serotonin operating in their system.
Oh, speaking of serotonin, although you may never think to get your hormone levels checked strictly to learn more about how you’re acting/reacting in your romantic relationship, I also found it interesting that people who have more dopamine in their system tend to take more risks when it comes to love while those who have more serotonin are usually far more cautious. Meaning, that how you are in your relationship(s) may not be just about your personality; your hormone levels tend to have a say as well.
8. Your Anterior Cingulate Cortex May Make You Obsessive
Your anterior cingulate cortex is the part of your brain that’s associated with things like motivation and action. Anyway, since overactivity in this part of the brain is oftentimes linked to things like obsessive-compulsive disorder, some researchers believe that the reason why some people seem to think obsessively about their partner, almost to the point of obsession, if they don’t stay on top of it, is because of how their brain reacts to their attachment to their partner. For the record, this is also the part of your brain that literally lights up whenever you see your partner, too.
9. Vagus Nerves “Sync Up”
Your vagus nerves are a part of your nervous system that starts at your brain and runs through your digestive tract. This makes them an integral part of things like your immunity, your speech, your moods, and your heart rate. As far as your brain goes, some studies reveal that after a couple has been together for a longer period of time, it’s not uncommon for their vagus nerves to “sync up” in the sense of having similar facial expressions and hand gestures being and even their hearts starting to beat at the same pace. As a direct result, the syncing makes it easier for both individuals to make sacrifices for one another in order to remain together. Share that with your grandparents the next time you see them. #wink
10. If You’ve Been Together for a While, Your Angular Gyrus Becomes Stronger
Speaking of longevity, another perk that comes with couples who choose to go the distance is the part of their brain known as their angular gyrus becomes more active. What’s actually sweet about this is that not only is this what makes it easier for you to learn complex languages, but you can also start to anticipate your partner’s actions with it too. As a direct result, science says that many couples can finish each other’s sentences — and it’s all because their angular gyrus has gotten stronger as a result of them staying committed.
____
After reading all of this, how could anyone possibly look at being in love casually? There are far too many intricate parts at work — yes, literally. Yeah, when Rihanna sang about having “love on the brain,” she said more than a mouthful…whether she realized it or not.
And if you declare that you are in love, make sure to factor in what your brain is going through. Then choose wisely. Even your brain and mental health depend on it. Also…literally.
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So, we handpicked one hundred It Girls who embody that palpable It Factor moving through us as young Black women, the kind of motion lighting up the world both IRL and across the internet.
It Girl 100 became xoNecole’s most successful program, with the hashtag organically reaching more than forty million impressions on Instagram in just twenty-four hours. Yes, it caught on like wildfire because we celebrated some of the most brilliant and influential GenZennial women of color setting trends and shaping culture. But more than that, it resonated because the women we celebrated felt seen.
Many were already known in their industries for keeping this generation fly and lit, but rarely received recognition or flowers. It Girl 100 became a safe space to be uplifted, and for us as Black women to bask in what felt like an era of our brilliance, beauty, and boundless influence on full display.
And then, almost overnight, it was as if the rug was pulled from under us as Black women, as the It Girls of the world.
Our much-needed, much-deserved season of ease and soft living quickly metamorphosed into a time of self-preservation and survival. Our motion and economic progression seemed strategically slowed, our light under siege.
The air feels heavier now. The headlines colder. Our Black girl magic is being picked apart and politicized for simply existing.
With that climate shift, as we prepare to launch our second annual It Girl 100 honoree list, our team has had to dig deep on the purpose and intention behind this year’s list. Knowing the spirit of It Girl 100 is about motion, sauce, strides, and progression, how do we celebrate amid uncertainty and collective grief when the juice feels like it is being squeezed out of us?
As we wrestled with that question, we were reminded that this tension isn’t new. Black women have always had to find joy in the midst of struggle, to create light even in the darkest corners. We have carried the weight of scrutiny for generations, expected to be strong, to serve, to smile through the sting. But this moment feels different. It feels deeply personal.
We are living at the intersection of liberation and backlash. We are learning to take off our capes, to say no when we are tired, to embrace softness without apology.
And somehow, the world has found new ways to punish us for it.
In lifestyle, women like Kayla Nicole and Ayesha Curry have been ridiculed for daring to choose themselves. Tracee Ellis Ross was labeled bitter for speaking her truth about love. Meghan Markle, still, cannot breathe without critique.
In politics, Kamala Harris, Letitia James, and Jasmine Crockett are dragged through the mud for standing tall in rooms not built for them.
In sports, Angel Reese, Coco Gauff, and Taylor Townsend have been reminded that even excellence will not shield you from racism or judgment.
In business, visionaries like Diarrha N’Diaye-Mbaye and Melissa Butler are fighting to keep their dreams alive in an economy that too often forgets us first.
Even our icons, Beyoncé, Serena, and SZA, have faced criticism simply for evolving beyond the boxes society tried to keep them in.
From everyday women to cultural phenoms, the pattern is the same. Our light is being tested.
And yet, somehow, through it all, we are still showing up as that girl, and that deserves to be celebrated.
Because while the world debates our worth, we keep raising our value. And that proof is all around us.
This year alone, Naomi Osaka returned from motherhood and mental health challenges to reach the semifinals of the US Open. A’ja Wilson claimed another MVP, reminding us that beauty and dominance can coexist. Brandy and Monica are snatching our edges on tour. Kahlana Barfield Brown sold out her new line in the face of a retailer that had been canceled. And Melissa Butler’s company, The Lip Bar, is projecting a forty percent surge in sales.
We are no longer defining strength by how much pain we can endure. We are defining it by the unbreakable light we continue to radiate.
We are the women walking our daily steps and also continuing to run solid businesses. We are growing in love, taking solo trips, laughing until it hurts, raising babies and ideas, drinking our green juice, and praying our peace back into existence.
We are rediscovering the joy of rest and realizing that softness is not weakness, it is strategy.
And through it all, we continue to lift one another. Emma Grede is creating seats at the table. Valeisha Butterfield has started a fund for jobless Black women. Arian Simone is leading in media with fearless conviction. We are pouring into each other in ways the world rarely sees but always feels.
So yes, we are in the midst of societal warfare. Yes, we are being tested. Yes, we are facing economic strain, political targeting, and public scrutiny. But even war cannot dim a light that is divinely ours.
And we are still shining.
And we are still softening.
And we are still creating.
And we are still It.
That is the quiet magic of Black womanhood, our ability to hold both truth and triumph in the same breath, to say yes, and to life’s contradictions.
It is no coincidence that this year, as SheaMoisture embraces the message “Yes, And,” they stand beside us as partners in celebrating this class of It Girls. Because that phrase, those two simple words, capture the very essence of this moment.
Yes, we are tired. And we are still rising.
Yes, we are questioned. And we are the answer.
Yes, we are bruised. And we are still beautiful.
This year’s It Girl 100 is more than a list. It is a love letter to every Black woman who dares to live out loud in a world that would rather she whisper. This year’s class is living proof of “Yes, And,” women who are finding ways to thrive and to heal, to build and to rest, to lead and to love, all at once.
It is proof that our joy is not naive, our success not accidental. It is the reminder that our light has never needed permission.
So without further ado, we celebrate the It Girl 100 Class of 2025–2026.
We celebrate the millions of us who keep doing it with grace, grit, and glory.
Because despite it all, we still shine.
Because we are still her.
Because we are still IT, girl.
Meet all 100 women shaping culture in the It Girl 100 Class of 2025. View the complete list of honorees here.
Featured image by xoStaff
This year's It Girl 100 is a mosaic of brilliance, spotlighting entrepreneurs, cultural disruptors, beauty visionaries, and boundary-pushing creatives who embody the spirit of "Yes, And." This digital celebration honors the women who embrace every facet of themselves, proving you can chase the bag and still honor your desire to live life softly.
Here's the roll call for xoNecole's It Girl 100 Class of 2025: Viral Voices.
Content Creator Eni Popoola
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Eni Popoola
Her Handle: @enipopoola
Her Title: Content Creator
Who's That It Girl: Eni Popoola is the visionary creative behind beautifully cinematic content that fuses fashion and feeling. We love her for proving that elegance and emotion can exist in every frame.
Her "Yes, And" Statement: "Yes, I'm not afraid to pivot and the best is still yet to come."
Content Creator Jessie Woo
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Jessie Woo
Her Handle: @thejessiewoo
Her Title: Content Creator
Who's That It Girl: Jessie Woo is joy personified, a multi-talented entertainer and fearless truth-teller. We celebrate her for using humor, music, and faith to create content that heals through laughter.
Her "Yes, And" Statement: "Yes. I’m a force — and that’s why I create my own lanes instead of waiting for one to open."
Media Personality, Founder and Host Kayla Nicole
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Kayla Nicole
Her Handle: @kaylanicole
Her Title: Media Personality; Founder, Tribe Therepē; Host, Welcome to the Pre-Game
Who's That It Girl: Kayla Nicole merges style, storytelling, and self-awareness like no other. We celebrate her for being the friend in our feeds who reminds us to show up fully, flaws, fire, and all.
Her "Yes, And" Statement: "Yes, I’m curating conversations on my podcast The Pre-Game, and cultivating community with my wellness brand Tribe Therepē."
Creator and Entrepreneur Simi Muhumuza
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Simi Muhumuza
Her Handle: @simimoonlight
Her Title: Creator and Entrepreneur
Who's That It Girl: Simi is a writer, and creative based in Brooklyn, NY. She focuses on style, lifestyle and wellness.
Her "Yes, And" Statement: "Yes, and I’m reaching even higher."
Creator Kiera Please
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Kiera Please
Her Handle: @kieraplease
Her Title: Creator
Who's That It Girl: Kiera Please is a creator, voice actress, and artist whose creativity knows no bounds. With her unique mix of style, cosplay, and storytelling, she’s built a global fan base that celebrates self-expression.
Her "Yes, And" Statement: "Yes, I’m just weird girl and I’ll just keep getting weirder."
Content Creator Zaynah Bear
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Zaynah Bear
Her Handle: @madame_zay
Her Title: Content Creator
Who's That It Girl: Zaynah Bear is a social media content creator known for her cartoon-style comedic storytelling that blends humor with everyday relatability. Her unique approach to creating content builds strong audience connections and keeps her community coming back for more laughs.
Her "Yes, And" Statement: "Yes, I'm boldly Black and beautifully quirky, owning every shade of my uniqueness."
Social Media Consultant and Creative Candace Marie
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Candace Marie
Her Handle: @marie_mag_
Her Title: Social Media Consultant and Creative
Who's That It Girl: Candace Marie is a luxury social-media strategist and founder of Black In Corporate. A former Parsons professor, she’s worked with fashion powerhouses like PRADA and Victoria Beckham, helping shape a more inclusive industry.
Her "Yes, And" Statement: "Yes, I’m grounded in strategy & storytelling—and I’m creating pathways for the future of influence."
Model and Content Creator Quenlin Blackwell
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Quenlin Blackwell
Her Handle: @quenblackwell
Her Title: Model and Content Creator
Who's That It Girl: Quenlin Blackwell is digital dynamite, witty, unfiltered, and wildly creative. We celebrate her for turning chaos into comedy and self-expression into art that connects millions.
Content Creator and TV Host Kamie Crawford
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Kamie Crawford
Her Handle: @kamiecrawford
Her Title: Content Creator and TV Host
Who's That It Girl: Kamie Crawford’s presence is as commanding as her compassion. We love her for being a media personality who advocates for confidence, self-worth, and love rooted in realness.
Her "Yes, And" Statement: "Yes, I'm that girl and I’ve had to heal parts of me to become her."
Author and Podcaster Sesali Bowen
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Sesali Bowen
Her Handle: @badfatblackgirl
Her Title: Author and Podcaster
Who's That It Girl: Sesali was born and raised on the Southside of Chicago and coined trap feminism. During her time as an entertainment writer for Refinery29 she was one of the architects of Unbothered, their sub brand for Black women. As a brand strategist and copywriter she’s worked with Netflix, Onyx Collective, and more.
Her "Yes, And" Statement: "Yes, I said it and I’m standing on it."
Co-Host of 'Pour Minds' Podcast Drea Nicole
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Drea Nicole
Her Handle: @dreanicoleee
Her Title: Co-Host of Pour Minds Podcast
Who's That It Girl: As one-half of the hit podcast Pour Minds, Drea Nicole brings real talk with humor and heart. We celebrate her for creating spaces where women can laugh, learn, and live out loud.
Co-Host of 'Pour Minds' Podcast Lex P
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Lex P
Her Handle: @lex_p_
Her Title: Co-Host of Pour Minds Podcast
Who's That It Girl: Lex P’s voice is bold, funny, and deeply authentic. We love her for turning the mic into a movement through Pour Minds, proving that humor and healing can thrive side by side.
Content Creator Jeannette Reyes
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Jeannette Reyes
Her Handle: @msnewslady
Her Title: Content Creator
Who's That It Girl: Jeannette Reyes, known online as @msnewslady, went from the newsroom to building her own media brand. She’s a creator, speaker, and author using her platform to help women show up confidently on and off camera.
Her "Yes, And" Statement: "Yes, I take up space and I make room for others."
Founder of Mary Louise Cosmetics Akilah Releford
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Akilah Releford
Her Handle: @akilahreleford
Her Title: Founder of Mary Louise Cosmetics
Who's That It Girl: Founder of Mary Louise Cosmetics, Akilah merges skincare and sisterhood with intention. We celebrate her for turning DIY passion into a thriving brand rooted in empowerment and care.
Award-Winning Journalist and Beauty Expert Kayla Greaves
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Kayla Greaves
Her Handle: @kaylaagreaves
Her Title: Award-Winning Journalist and Beauty Expert
Who's That It Girl: Kayla Greaves is a journalist and on-camera expert who’s spent more than a decade telling stories that matter. From interviewing icons like Naomi Campbell to consulting for major brands, she continues to redefine beauty and culture.
Her "Yes, And" Statement: "Yes, I'm bold and I make no qualms about it."
Digital Creator Lauren W.
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Lauren W.
Her Handle: @laurenthelolife
Her Title: Digital Creator, Lifestyle and Beauty
Who's That It Girl: Lauren W. brings a breath of honesty to lifestyle content. We celebrate her for creating digital spaces that feel like safe havens for self-discovery, growth, and grace.
Her "Yes, And" Statement: "Yes, and I'll do it solo!"
Host of 'She's So Lucky' Podcast Les Alfred
Les Alfred
Her Handle: @lesalfred
Her Title: Host of She's So Lucky podcast
Who's That It Girl: Les Alfred is a media entrepreneur and cultural storyteller shaping the future of women-centered narratives. As the creator and host of She’s So Lucky (formerly Balanced Black Girl), an NAACP Image Award-nominated podcast, she has built a thriving media ecosystem that explores wellness and self-discovery through the lens of trail-blazing women.
Her "Yes, And" Statement: "Yes, I'm strong and I lead with softness."
Influencer, Rapper and Actress Aliyah's Interlude
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Aliyah's Interlude
Her Handle: @aliyahsinterlude
Her Title: Influencer, Rapper and Actress
Who's That It Girl: Aliyah's Interlude brings softness and soul to the internet’s boldest spaces. We honor her for creating artful, introspective content that reminds us to slow down, reflect, and dream louder.
Beauty and Fashion Digital Creator Clarke Peoples
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Clarke Peoples
Her Handle: @clarkepeoples
Her Title: Beauty and Fashion Digital Creator
Who's That It Girl: Clarke Peoples creates content that feels like a warm conversation. We love her for her authenticity and for showing that influence grounded in truth never goes out of style.
Model and Content Creator Kamrin White
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Kamrin White
Her Handle: @kamrinwhite
Her Title: Model and Content Creator
Who's That It Girl: We celebrate Kamrin White for transforming her lifestyle lens into something real and radiant. A proud Afro-Latina creator and entrepreneur, she weaves wellness, fashion, and authenticity into her content, inviting her audience to live boldly and vulnerably in their own stories.
Lifestyle and Beauty Creator Jayla Brenae
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Jayla Brenae
Her Handle: @jaylabrenae
Her Title: Lifestyle and Beauty Creator
Who's That It Girl: Jayla Brenae inspires through her transparency and storytelling. We honor her for blending wellness, confidence, and community into content that uplifts and empowers women of all walks.
Journalist and Content Creator Casey Winbush
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Casey Winbush
Her Handle: @caseywinbush
Her Title: Journalist and Content Creator
Who's That It Girl: With humor and heart, Casey Winbush is the voice of digital relatability. We celebrate her for blending vulnerability with wit, turning everyday stories into shared laughter and healing.
Model and Owner of PLEASEPEARLME Kendra Austin
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Kendra Austin
Her Handle: @kendramorous
Her Title: Model and Owner of PLEASEPEARLME
Who's That It Girl: Kendra Austin is poetry in motion, writer, model, and muse. We honor her for redefining softness as strength and for giving women permission to rest, feel, and reclaim joy.
Multidisciplinary Visual Artist and Creative Entrepreneur Shema Love
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Shema Love
Her Handle: @shemalove
Her Title: Multidisciplinary Visual Artist and Creative Entrepreneur
Who's That It Girl: Shema Love is a Brooklyn-based artist and designer turning art into healing. Her bold visuals and apparel celebrate Black joy, creativity, and self-expression, featured by Vogue, Nike, Netflix, and the WNBA.
Her "Yes, And" Statement: "Yes, I save lives and art saved me."
Content Creator Kristine Thompson
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Kristine Thompson
Her Handle: @mskristine
Her Title: Content Creator
Who's That It Girl: Kristine Thompson is a fashion and lifestyle creator passionate about redefining style standards for plus-size women. Through her platforms, she shares inspiring fashion, beauty, and travel content that empowers her community to feel confident at any size.
Her "Yes, And" Statement: "Yes, I celebrate style and I challenge the idea that beauty comes in one size."
Beauty, Lifestyle and Fashion Creator Crystal Nicole
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Crystal Nicole
Her Handle: @iamcrystalnicolee
Her Title: Beauty, Lifestyle and Fashion Creator
Who's That It Girl: Crystal Nicole’s storytelling moves between vulnerability and victory. We honor her for her ability to inspire others to be unapologetically themselves despite the pressures of social media and for crafting narratives that empower women to rewrite their own anthems.
Tap into the full It Girl 100 Class of 2025 and meet all the women changing game this year and beyond. See the full list here.
Featured image by xoStaff